Clostridium difficile infection at a tertiary care hospital in south India.

Changing trends of clostridium difficile associated diarrhoea (cdad) in a tertiary care hospital in kolkata, india

Introduction In this era of increased and indiscriminate antibiotic usage, it is not only the advent of multi-drug resistant pathogens, but also the rising prevalence of Clostridium difficile Associated Diarrhoea (CDAD) which is drawing concern world-wide. It is important not only to implement a comprehensive antibiotic policy, but also to take up stringent infection control measures to curb th...

Molecular Analysis of Toxigenic Clostridium difficile Isolates from Hospital Environment by PCR Ribotyping Method

Background and Aims: Clostridium difficile is an identified cause of antibiotic-associated diarrhea, antibiotic-associated colitis, pseudomembranous colitis and nosocomial diarrhea. The objective of this survey was to determine molecular analysis of toxigenic Clostridium difficile isolates from hospital environment in Tehran tertiary medical centers. Materials and Methods: In this descriptiv...

Evolution of Testing Algorithms at a Tertiary Care Hospital for the Detection of Clostridium difficile Infections

Toxinotyping and Sequencing of Clostridium difficile Isolates from Patients in a Tertiary Care Hospital of Northern India

BACKGROUND Clostridium difficile is an important cause of infectious colitis among hospitalized patients across the globe. The pathogenic potential of C. difficile in producing significant morbidity and mortality is mainly due to production of toxins A and B. The outbreaks of C. difficile infection (CDI) are due to changes in the genetic sequences of the organism. There is hardly any molecular ...

Surveillance for Antibiotic Resistance in Clostridium difficile Strains Isolated from Patients in a Tertiary Care Center

Clostridium difficile is the major etiological agent of nosocomial diarrhea primarily precipitated by antimicrobial therapy. We prospectively investigated the antibiogram profile of C. difficile strains isolated from patients reporting to a tertiary care hospital in North India. Fecal samples obtained from 1110 suspected cases of C. difficile infection were cultured for isolation of C. difficil...